Dr. Sadhana Ramchandra Joshi

Profile

Date of Birth: 24/10/1962

Qualification: M. Sc. Ph.D (Biochemistry)

Designation: Professor, and Head,Nutritional Medicine Division

Contacts

e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Phone: 020-24366920 (ext.301)

Research experience: 23 years

Area of interest: Maternal and Child Health, Nutrition, Epigenetics

Honors/Awards

Awards

  • Research Excellence Award for Developing Country Scientist at the 7th World Congress on Developmental Origins of Health and Disease, held in September 18-21, 2012, in Portland, OR, USA
  • “Best Researcher Award” at the 15th Foundation day Ceremony at Bharati Vidyapeeth University, Pune, 26th April, 2010 at the hands of Chairman, University Grants Commision, Dr. Sukhdeo Thorat
  • Member of an Advisory Committee on Pediatric and Maternal Nutrition and Health. DSM, Nutritional Products USA February 16, 2016, Columbia, MD, USA.
  • Nominated to be part of an Expert Group formed to give recommendations to the State Project Directorate, Rashtriya Uchchatar Shiksha Abhiyan RUSA, Department of Higher & Technical Education, Government of Maharashtra on Value Added Courses for emerging & high demand sector of Wellness.
  • Invitation to participate in the 2016 Grand Challenges Meeting sponsored by Bill & Melinda Gates Foundation at QEII Conference Centre, London, England (23rd – 28th October, 2016).

Invited Talks:

  • Delivered a talk on the topic “Emerging trend of Omega 3 fatty acids in the field of therapeutics” at the AICTE sponsored two weeks Quality Improvement Programme on “Emerging Trends in Pharmacological Research: Convergence of Molecular Targets” organized by Poona College of Pharmacy, Bharati Vidyapeeth University (19th – 31st December, 2016).
  • Delivered a talk on the topic “Prenatal Maternal Nutrition" at the workshop "Securing Our Children's Future: Nutrition and Immunity for Infant and Child Health" organised by MSD Wellcome Trust Hilleman Laboratories Pvt. Ltd. New Delhi. (21st - 22nd September 2016).
  • Delivered a talk on the topic “Maternal Sex Specific Differences in Fetal Programming for Adult Diseases at First mysore international conference on medical and social sciences Theme gender equity: social issues and health challenges in today's context" (24th-27th November 2015)
  • “Altered Maternal Nutrition (Folic Acid, Vitamin B12 and Omega-3 Fatty Acids) and Risk for Non-communicable Diseases in the Offspring in Later Life” at International Congress on Obesity and Metabolic Syndrome in conjunction with the 43rd Annual Scientific Meeting of KSSO organized by ICOMES, Seoul, Korea (12th-14th November 2015).
  • “Nutrigenomics Mechanisms and consequences” at Abhyas Mahotsav, Mumbai (5th February, 2015).
  • “Nutrigenomics in pregnancy” at Nirmala Niketan (5th February, 2015).
  • “Maternal Nutrition and its effect on health of the next generation” at the 102nd Indian Science Congress, Mumbai (3rd -7th January 2015).
  • “Mechanism Underlying the Association of Maternal Nutrition (folic acid, vitamin B12, and Omega 3 fatty acids) and Risk for Diseases in Later Life” at the 18th Annual Meeting of SNEHA, Lonavala (26th – 28th September 2014).
  • “Maternal Nutrtion, Epigenetics and Adult Health” at the Plenary Session at the Indian Dietetic Association (IDA) conference, Pune (12th-14th Dec 2013).
  • “Maternal Diet Induced Systemic and Intrauterine Inflammation: Risk for Non-communicable Disease in the Offspring” at 45th National Conference of the Nutrition Society of India at Hyderabad (20th-21st Nov 2013).
  • “Asian perspective on PUFA supply in pregnancy infants: review of evidence and proposed recommendations” at “Asia Pacific Workshop on Polyunsaturated fatty acids” at Singapore (15th-17th Nov 2013).
  • “Epigenetic influence on young India” at West Zone YUVA FOGSI Conference, Bhopal (6th-8th Sept 2013).
  • “Maternal micronutrients in the one carbon cycle and epigenetic programming” at the C.S.I.R - Institute of Genomics and Integrative Biology (8th-10th March 2013).
  • “Enhancing Health, Well-being and Sustainability - Opportunities, Challenges and Future Directions at International Conference (10th–12th Jan 2013)
  • World Congress-BCGIP, India & 2nd Annual Congress of Society of Fetal Medicine (16th-18th Nov 2012).
  • “A disturbed Pregnancy” Conference at Bangalore. Organized by the Federation of Obstetrics and Gynecologists, Bangalore (11th Aug 2012)
  • “Role of women for a healthy society” at Tata Institute of Social Sciences, Platinum Jubilee Year, Symposium on Food security, nutrition, the environment and survival., Mumbai (18th Feb 2012)
  • “Maternal and Child Health Care with Specific reference to Nutrition and Nutrition Security” at Indian Science Congress, Bhubaneswar, Orissa (3rd-7th Jan, 2012)
  • Indo-UK workshop at National Institute of Nutrition Sponsored by Wellcome Trust UK. 3-day Indo-UK workshop at NIN, Hyderabad on the 8th -10th September, 2011 to plan longitudinal studies on infant feeding, child growth, development and adult health outcomes.
  • “Possible Mechanisms of Altered Maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acid Metabolism in DOHaD: Use of Rat Models” at the ICMR centenary celebrations National Institute of Nutrition organized Seminar (one day)/brain storming session (half a day) Maternal under-nutrition and developmental origins of health and disease (25th -26th June, 2011).
  • “Nutraceutical approach for better pregnancy outcome and prevention of diseases” at Innovations in Pharmacology, Bharati Vidyapeeth University (22nd Nov- 4th Dec, 2010).
  • “Omega 3 fatty acids and antioxidants: Nutraceutical approach to better pregnancy outcome” 5th nutraceutical summit at India’s biggest nutraceutical, functional foods, dietary supplements and ingredients show, New Delhi (28th -30th Oct, 2009).

Other activities (Please do not mention PhD guide ship and experience of writing proposals)

  • DBT task force member on the task force “Human Development Disease Biology”
  • Reviewer for Project Grants from countries like France and Netherlands
  • Editorial board member of “Journal of Nutrition & Intermediary Metabolism”, ELSEVIER
  • Reviewer for many International Scientific Journals with high impact factor
  • Ethical Committee Member (Bharati Vidyapeeth Medical College)

Professional memberships

  • Fellow of the Society of Applied Biotechnologists
  • Member of the Board of The India Chapter of Gestosis, The Indian Society of Preeclampsia
  • Life member of the International Society for Developmental Origins of Health and Disease
  • Life member of Nutrition Society of India, India
  • Life member of Society for the Natal effects on Health in Adults, India

Publications

  • Total 117
  • International: 111
  • National: 6
  • Book Chapters : 5

Research Programmes

The theme of my research is mother and child health which addresses the importance of maternal nutrition, with special reference to micronutrients and risk of developing metabolic/neurodevelopmental disorders in childhood and later life. My main focus is on maternal omega-3 fatty acids, folic acid and vitamin B12 since these micronutrients are the key constituents of one carbon metabolism which influence DNA and chromatin methylation patterns. A disturbed one carbon metabolism due to maternal micronutrient imbalance may lead to altered epigenetic programming in the fetus with implications for non-communicable diseases in later life.

At IRSHA I initiated the work on mother and child health in collaboration with the clinicians from Bharati Hospital on pregnancy related disorders (preeclampsia, preterm labor). The incidence of these pregnancy complications are alarmingly increasing in developing countries like India making it an important health issue. However, the mechanisms responsible for the pathogenesis of these complications have not been completely understood. Animal models are also used to validate the mechanisms of interactions of micronutrients during pregnancy and their role in fetal programming for adult diseases.

Publications

  1. Mary S, Kulkarni MJ, Mehendale SS, Joshi SR, Giri AP. Differential accumulation of vimentin fragments in pre-eclamptic placenta. Cytoskeleton (Hoboken). 2017 (In press).
  2. Chopra HV, Kehoe SH, Sahariah SA, Sane HN, Cox VA, Tarwade DV, Margetts BM, Potdar RD, Fall CHD and Joshi SR. Effect of a daily snack containing green leafy vegetables on women’s fatty acid status; a randomized controlled trial in Mumbai, India. Asia Pacific Journal of Clinical Nutrition 2017 (In press).
  3. Sahay A, Jadhav A, Sundrani S, Wagh G, Mehendale S, Chavan-Gautam P, Joshi S. VEGF and VEGFR1 levels in different regions of the normal and preeclampsia placentae. Molecular and Cellular Biochemistry 2017 (Accepted)
  4. Ashok Pranita, Balsubramanian Bhawani, Joshi Sadhana, Kharche J, Vidya SM. Associations of vitamin D with metabolic syndrome components in Indian urban middle aged women. Natl J Physiol Pharm (2017).
  5. Ashok Pranita, Balsubramanian B, Joshi Sadhana, Wagh Girija, Vidya SM. Prevalence of metabolic syndrome in urban middle aged women. International Journal of Scintific Research. (2017). 6 (7). 2277-8179.
  6. Khot V, Yadav D, Shrestha S, Kaur L, Sundrani D, Chavan-Gautam P, Mehendale S, Chandak G, Joshi S. Hypermethylated CpG sites in the MTR Gene Promoter in Preterm Placenta. Epigenomics (2017) (IF: 4.044)
  7. Mary S, Kulkarni MJ, Mehendale SS, Joshi SR, Giri AP. Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women. Clinical Proteomics. 2017 Mar 21;14(1):8.(IF:3.476)
  8. Sundrani Deepali, Roy Suchitra, Jadhav Anjali, Joshi Sadhna. (2017). Sex-Specific Differences and Developmental Programming for Diseases in Later Life. Reproduction, Fertility and Development. (Accepted)( (IF:3.184)
  9. Nandi AA, Wadhwani NS, Joshi SR. Altered Metabolic Homeostasis between Vitamin D and Long Chain Polyunsaturated Fatty Acids in Preeclampsia. Med Hypotheses. 2017;100:31-36. (IF: 1.136)
  10. Mary S, Kulkarni MJ, Malakar D, Joshi SR, Mehendale SS, Giri AP. Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers I nplasma. Journal of Proteome Research. 2016. [In Press] (IF: 4.173)
  11. Dangat K, Upadhyay D, Kilari A, Sharma U, Kemse N, Mehendale S, Lalwani S, Wagh G, Joshi S, Jagannathan NR. Altered breast milk components in preeclampsia; An in-vitro proton NMR spectroscopy study. International Journal of Clinical Chemistry and Diagnostic Laboratory Medicine. 2016;463:75-83. (IF: 2.7999)
  12. Khot VV, Chavan-Gautam P, Mehendale S, Joshi SR. Variable Methylation Potential in Preterm Placenta: Implication for Epigenetic Programming of the Offspring. Reproductive sciences. [In Press] (IF: 2.429)
  13. Rathod R, Khaire A, Kale A, Joshi S. A combined supplementation of vitamin B 12 and n-3 polyunsaturated fatty acids across two generations improves nerve growth factor and vascular endothelial growth factor levels in the rat hippocampus. Neuroscience. 2016 Dec 17;339:376-84. (IF: 3.231)
  14. Khaire A, Rathod R, Kale A, Joshi S. Vitamin B12 Deficiency Across Three Generations Adversely Influences Long-chain Polyunsaturated Fatty Acid Status and Cardiometabolic Markers in Rats. Archives of Medical Research. 2016;47(6):427-435. (IF: 2.12)
  15. Jawale S, Pulwale A, Joshi S, Kale A. Maternal High Fat Diet Deficient in Vitamin B12 Influences Long Chain Polyunsaturated Fatty Acid Composition in Rats. The Journal of Maternal-Fetal & Neonatal Medicine. [In Press] (IF: 1.08)
  16. Rathod RS, Khaire AA, Kale AA and Joshi SR. Effect of vitamin B12 and omega-3 fatty acid supplementation on brain neurotrophins and cognition in rats: A multigenerational study. Biochimie. 2016;128:201-8 (IF: 2.96)
  17. Khaire AA, Rathod RS, Kale AA and Joshi SR. A combined supplementation of vitamin b12 and omega-3 fatty acids across two generations improve cardiometabolic variables in rats. Food & Function. 2016 Sep 14;7(9):3910-9.(IF: 2.686)
  18. Kemse NG, Kale AA and Joshi SR. Maternal supplementation of omega-3 fatty acids and micronutrients reduces cardiometabolic variables in pregnancy induced hypertension rats. Life Sciences 2016;155:85-93 (IF: 2.680)
  19. Rani Alka, Wadhwani Nisha, Joshi Sadhana, Chavan Preeti. Altered development and function of the placental regions in preeclampsia and its association with long chain polyunsaturated fatty acids. Developmental Biology. 2016 Sep;5(5):582-97 (IF: 3.155)
  20. Meher Akshaya, Wadhwani Nisha, Joshi Sadhana. Placental DHA and mRNA Levels of PPARγ, LXRα and their Relationship to Birth Weight, Journal of Clinical Lipidology. 2016;10(4):767-74 (IF: 4.906)
  21. Meher Akshaya, Joshi Sadhana. Maternal Fatty Acids and Their Association with Birth Outcome: A Prospective Study. PLOS ONE. 2016;11(1):e0147359. (IF: 3.54)
  22. Kemse Nisha, Kale Anvita, Joshi Sadhana. Supplementation of maternal omega-3 fatty acids to pregnancy induced hypertension Wistar rats improves IL10 and VEGF levels. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2016;104:25-32. (IF: 3.155)
  23. Wadhwani Nisha, Narang Ankita, Mehendale Savita, Wagh Girija, Gupte Sanjay, Joshi Sadhana. Reduced maternal erythrocyte long chain polyunsaturated fatty acids exist in early pregnancy in preeclampsia. Lipids. 2016;51(1):85-94. (IF: 1.892)
  24. Wadhwani Nisha, Patil Vidya, Mehendale Savita, Wagh Girija, Gupte Sanjay, Joshi Sadhana. Increased homocysteine levels exist in women with preeclampsia from early pregnancy. J Matern Fetal Neonatal Med. 2016;29(16):2719-25. (IF: 1.370)
  25. Rathod RS, Kale AA and Joshi SR. Novel insights into the effect of vitamin B12and omega-3 fatty acids on brain function (Review). J Biomed Sci. 2016;23:17. (IF: 2.760).
  26. D'Souza Vandita, Kilari Anitha, Pisal Hemlata, Patil Vidya, Mehendale Savita, Wagh Girija, Gupte Sanjay, Joshi Sadhana. Maternal Nerve Growth Factor Levels during Pregnancy in Women with Preeclampsia: A Longitudinal Study. Int J Dev Neurosci. 2015;47(Pt B):340-6. (IF: 2.380)
  27. D'Souza Vandita, Rani Alka, Patil Vidya, Pisal Hemlata, Randhir Karuna, Mehendale Savita, Wagh Girija, Joshi Sadhana. Increased oxidative stress from early pregnancy in women who develop preeclampsia. Clinical and Experimental Hypertension. 2016;38(2):225-32. (IF: 1.234)
  28. Sahay AS, Sundrani DP and Joshi SR. Regional changes of placental vascularization in preeclampsia: A review. IUBMB Life. 2015;67(8):619-25. (IF: 3.143)
  29. Rathod RS, Khaire AA, Kale AA and Joshi SR. Beneficial effects of omega-3 fatty acids and vitamin B12 supplementation on brain docosahexaenoic acid, brain derived neurotrophic factor, and cognitive performance in the second-generation Wistar rats. Biofactors. 2015;41(4):261-72. (IF: 4.504)
  30. Sahay AS, Sundrani DP, Wagh GN, Mehendale SS and Joshi SR. Neurotrophin levels in different regions of the placenta and their association with birth outcome and blood pressure. Placenta. 2015;36(8):938-43. (IF: 2.972)
  31. Alka Rani, Preeti Chavan-Gautam, Savita Mehendale, Girija Wagh, Sadhana Joshi. Differential regional fatty acid distribution in normotensive and preeclampsia placenta. BBA Clinical. 2015: 4(0): 21-26.(IF:0.342)
  32. Meher A, Sundrani D, Joshi S. Maternal nutrition influences angiogenesis in the placenta through peroxisome proliferator activated receptors: A novel hypothesis. Mol Reprod Dev. 2015;82(10):726-34. (IF: 2.141)
  33. Wadhwani N, Pisal.H, Mehendale.S, Joshi S. (2015) A prospective study of maternal fatty acids, micronutrients and homocysteine and their association with birth outcome. Matern Child Nutr, 11(4), 559-573. (IF:3.060)
  34. Rathod RS, Khaire AA, Kale AA and Joshi SR. Maternal omega-3 fatty acid supplementation to a vitamin B12 deficient diet normalizes angiogenic markers in the pup brain at birth. Int J Dev Neurosci. 2015;43:43-9. (IF: 2.380)
  35. Khaire A, Rathod R, Kale A and Joshi S. Vitamin B12 and omega-3 fatty acids together regulate lipid metabolism in Wistar rats. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2015;99:7-17. (IF 3.155)
  36. Khaire AA, Kale AA and Joshi SR. Maternal omega-3 fatty acids and micronutrients modulate fetal lipid metabolism: A review. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2015;98:49-55. (IF: 3.155)
  37. Sahay AS, Sundrani DP, Wagh GN, Mehendale SS and Joshi SR. Regional differences in the placental levels of oxidative stress markers in pre-eclampsia. Int J Gynaecol Obstet. 2015;129(3):213-8. (IF: 1.674)
  38. Kemse NG, Kale AA and Joshi SR. A combined supplementation of omega-3 Fatty acids and micronutrients (folic Acid, vitamin B12) reduces oxidative stress markers in a rat model of pregnancy induced hypertension. PLoS One. 2014;9(11):e111902. (IF: 3.54)
  39. Roy S, Dhobale M, Dangat K, Mehendale S, Lalwani S and Joshi S. Differential oxidative stress levels in mothers with preeclampsia delivering male and female babies. J Matern Fetal Neonatal Med. 2015;28(16). (IF: 1.674)
  40. Khot V, Chavan-Gautam P, Joshi S. (2014) Proposing interactions between maternal phospholipids and the one carbon cycle: A novel mechanism influencing the risk for cardiovascular diseases in the offspring in later life. Life Sciences (Life Sci. 2014 Oct 2. pii: S0024-3205(14)00799-1). (IF: 2.685)
  41. Roy S, Dhobale M, Dangat K, Mehendale S, Wagh G, Lalwani S, Joshi S. (2014) Differential levels of long chain polyunsaturated fatty acids in women with preeclampsia delivering male and female babies. Prostaglandins leukotrienes and essential fatty acids (Prostaglandins Leukot Essent Fatty Acids. 2014 Jul 12. pii: S0952-3278(14)00100-8). (IF:3.155)
  42. Koletzko B, Boey C, Campoy C, Carlson S, Chang N, Guillermo-Tuazon MA, Joshi S, Prell1 C, Quak SH, Sjarif D, Supapannachart S, Yamashiro Y, Osendarp S. (2014) Current information and Asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy. Systematic review and practice recommendations from an Early Nutrition Academy workshop. Ann Nutr Metab (Ann Nutr Metab.2014;65(1):49-80). (IF:2.461)
  43. D'Souza V, Patil V, Pisal H, Randhir K, Joshi A, Mehendale S, Wagh G, Gupte S, Joshi S. (2014) Levels of brain derived neurotrophic factors across gestation in women with preeclampsia. Int J Dev Neurosci (Int J Dev Neurosci. 2014 Oct;37:36-40). (IF:2.380)
  44. Wadhwani N, Patil V, Pisal H, Joshi A, Mehendale S, Gupte S, Wagh G, Joshi S (2014). Altered maternal proportions of long chain polyunsaturated fatty acids and their transport leads to disturbed fetal stores in preeclampsia. Prostaglandins leukotrienes and essential fatty acids (2014 Jul-Aug;91(1-2):21-30). (IF: 3.155)
  45. Khot V, Kale A, Joshi A, Chavan-Gautam P, Joshi S. (2014) Expression of genes encoding enzymes involved in the one carbon cycle in rat placenta is determined by maternal micronutrients (Folic acid, Vitamin B12) and omega-3 fatty acids. Biomed Research International (Biomed Res Int. 2014;2014:613078). (IF:2.134)
  46. Sundrani DP, Reddy US, Chavan-Gautam PM, Mehendale SS, Chandak GR, Joshi SR. (2014) Altered methylation and expression patterns of genes regulating placental angiogenesis in preterm pregnancy. Reproductive Sciences. 21(12):1508-17. (IF:2.429)
  47. Meher A, Joshi A, Joshi S. (2014) Differential regulation of hepatic transcription factors in the wistar rat offspring born to dams fed folic acid, vitamin B12 deficient diets and supplemented with omega 3 fatty acids. PLoS One. (2014 Feb 28;9(2):e90209). (IF:3.54)
  48. Sahay A, Patil V, Sundrani D, Joshi A, Wagh G, Gupte S, Joshi S. (2014) A longitudinal study of circulating angiogenic, anti-angiogenic factors and AT1-AA levels in preeclampsia. Hypertens Res. (2014 Aug;37(8):753-8). (IF:3.208)
  49. Kilari A, Deshpande M, Joshi S. (2014) A novel molecular mechanistic hypothesis to validate the therapeutic effects of Tribulus terrestris (Gokshur) to ameliorate pathophysiology and improve pregnancy and fetal outcome in preeclampsia. Gynecol obstet. 4: 195. (IF:1.52)
  50. Sable P, Kale A, Joshi A, Joshi S. (2014) Maternal micronutrient imbalance alters gene expression of BDNF, NGF, TrkB and CREB in the offspring brain at an adult age. Int J Dev Neurosci. (Int J Dev Neurosci. 2014 May;34:24-32). (IF:2.380)
  51. Meher A, Joshi A, Joshi S. (2014) Maternal micronutrients, omega-3 fatty acids and placental PPARγ expression. Appl Physiol Nutr Metab. (2014 Jul;39(7):793-800). (IF:2.340)
  52. Dangat K, Kilari A, Mehendale S, Lalwani S, Joshi S. (2013) Preeclampsia alters milk neurotrophins and long chain polyunsaturated fatty acids. Int J Dev Neurosci. (Int J Dev Neurosci. 2014 Apr;33:115-21). (IF:2.380)
  53. Rathod R, Khaire A, Kemse N, Kale A, Joshi S. (2014) Maternal omega-3 fatty acid supplementation on vitamin B12 rich diet improves brain omega-3 fatty acids, neurotrophins and cognition in the Wistar rat offspring. Brain Dev. (Brain Dev. 2014 Jan 10. pii: S0387-7604(13)00350-1.). (IF:1.785)
  54. Sable P, Randhir K, Kale A, Chavan-Gautam P, Joshi S. (2015) Maternal micronutrients and brain global methylation patterns in the offspring. Nutr Neurosci.Jan 18(1):30-6. (IF: 2.274)
  55. Khaire A, Rathod R, Kemse N, Kale A, Joshi S. (2013) Supplementation of omega-3 fatty acids during gestation and lactation to vitamin B12 deficient/ supplemented diet improves pregnancy outcome and metabolic variables in Wistar rats. Reprod Fertil Dev. Jan 27 (2):341-50. (IF:2.400)
  56. Dhobale M, Pisal H, Mehendale S, Joshi S. (2013) Differential expression of human placental neurotrophic factors in preterm and term deliveries. Int J Dev Neurosci. (2013 Dec;31(8):719-23). (IF:2.380)
  57. Sable P, Kale A, Joshi S. (2013) Prenatal Omega 3 fatty acid supplementation to a micronutrient imbalanced diet protects brain neurotrophins both in the cortex and hippocampus in the adult rat offspring. Metabolism. (2013 Nov;62(11):1607-22). (IF:4.375)
  58. Sundrani DP, Reddy US, Joshi AA, Mehendale SS, Chavan-Gautam PM, Hardikar AA, Chandak GR, Joshi SR. (2013) Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clin Epigenetics. (2013 Apr 26;5(1):6). (IF:4.543)
  59. D'Souza VA, Kilari AS, Joshi AA, Mehendale SS, Pisal HM, Joshi SR. (2014) Differential regulation of brain-derived neurotrophic factor in term and preterm preeclampsia. Reprod Sci. (2014 Feb;21(2):230-5). (IF: 2.429)
  60. Roy S, Sable P, Khaire A, Randhir K, Kale A, Joshi S (2013). Effect of maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acids on indices of brain oxidative stress in the offspring. Brain Dev. March 36(3):219-27. (IF:1.785)
  61. Sundrani D, Chavan P, Pisal H, Mehendale S, Joshi S. (2013). Matrix metalloproteinases-2, -3 and tissue inhibitors of metalloproteinases -1, -2 in placentas from preterm pregnancies. Reproduction (2013 Apr 15;145(4):401-10). (IF:3.184)
  62. D’Souza V, Chavan-Gautam P, Joshi S. (2013) Counteracting oxidative stress in pregnancy through modulation of maternal micronutrients and omega-3 fatty acids. Curr Med Chem. (2013;20(37):4777-83). (IF:3.850)
  63. Wadhwani N, Dangat K, Joshi A, Joshi S. (2013) Maternal micronutrients and omega 3 fatty acids affect placental fatty acid desaturases and transport proteins in wistar rats. Prostaglandins Leukot Essent Fatty Acids. (2013 Mar;88(3):235-42). (IF:3.155)
  64. Dangat K, Kilari A, Mehendale S, Lalwani S, Joshi S. (2013) Higher levels of brain derived neurotrophic factor but similar nerve growth factor in human milk in women with preeclampsia. Int J Dev Neurosci. (2013 May;31(3):209-1). (IF:2.380)
  65. Sundrani D, Khot V, Pisal H, Mehendale S, Wagh G, Joshi A, Joshi S. (2013) Gestation dependant changes in angiogenic factors and their associations with birth measures in normotensive pregnancy. PLoS One. (2013;8(1):e54153). (IF:3.54)
  66. Meher A, Joshi A, Joshi S. (2013) Preconceptional fish oil supplementation on a micronutrient deficient diet improves reproductive cycles in Wistar rats” Reprod Fertil Dev. (2013 Aug;25(7):1085-94). (IF:2.400)
  67. Sable P, Dangat K, Joshi A, Joshi S. (2012) Maternal omega 3 fatty acid supplementation during pregnancy to a micronutrient imbalanced diet protects postnatal reduction of brain neurotrophins in the rat offspring. Neuroscience (2012 Aug 16;217:46-55). (IF:3.231)
  68. Dhobale M, Mehendale S, Pisal H, D’Souza Vand, Joshi S. (2012). Association of brain derived neurotrophic factor and tyrosine kinase B receptor in pregnancy Neuroscience. (2012 Aug 2;216:31-7). (IF:3.231)
  69. Dhobale M, Chavan P, Kulkarni A, Mehendale S, Pisal H and Joshi S. (2012). Reduced Folate, Increased Vitamin B12 and Homocysteine Concentrations in Women Delivering Preterm. Ann Nutr Metab. (2012;61(1):7-14). (IF:2.620)
  70. Mary S, Patil G, Kulkarni A, Kulkarni M, Joshi S., Mehendale S, Giri A (2012). Dynamic proteome in enigmatic preeclampsia discovery: An account of molecular mechanisms and biomarker. Proteomics Clin Appl. (2012 Jan;6(1-2):79-90). (IF:2.960)
  71. Dhobale M, Mehendale S, Pisal H, Joshi S. (2012) Reduced maternal and cord nerve growth factor levels in preterm deliveries. Int J Dev Neurosci. (2012 Apr;30(2):99-103). (IF:2.380)
  72. Sundrani D, Chavan Gautam P, Pisal H, Mehendale S, Joshi S. (2012) Matrix metalloproteinase-1 and -9 in human placenta during spontaneous vaginal delivery and caesarean sectioning in preterm pregnancy. PLoS One. (2012 Jan;7(1):e29855). (IF:3.54)
  73. Wadhwani N, Manglekar R, Dangat K , Kulkarni A, Joshi S. (2011) Effect of maternal micronutrients (folic acid, vitamin B12) and omega 3 fatty acids on liver fatty acid desaturases and transport proteins in Wistar rats. Prostaglandins Leukot Essent Fatty Acids. (2012 Jan-Feb;86(1-2):21-7). (IF:3.155)
  74. Sundrani D, Chavan Gautam P, Mehendale S, Joshi S. (2011) Altered metabolism of maternal micronutrients and omega 3 fatty acids epigenetically regulate matrix metalloproteinases in preterm pregnancy: A novel hypothesis. Med Hypotheses. (2011 Nov;77(5):878-83). (IF:1.136)
  75. Dhobale M, Wadhwani N, Mehendale S, Pisal H, Joshi S. (2011) Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries. Prostaglandins Leukot Essent Fatty Acids. (2011 Sep-Oct; 85(3-4):149-53). (IF:3.155)
  76. Sable P, Dangat K, Kale A, Joshi S. (2011) Altered brain neurotrophins at birth: consequence of imbalance in maternal folic acid and vitamin B12 metabolism. Neuroscience. (2011 Sep 8;190:127-34). (IF:3.231)
  77. Dhobale M, Joshi S. (2012) Altered maternal micronutrients (folic acid, vitamin B12) and omega 3 fatty acids through oxidative stress may reduce neurotrophic factors in preterm pregnancy. J Matern Fetal Neonatal Med. (2012 Apr;25(4):317-23). (IF:1.370)
  78. Roy S, Kale A, Dangat K, Sable P, Kulkarni A, Joshi S. (2012) Maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acids: Implications for neurodevelopmental risk in the rat offspring. Brain Dev. (2012 Jan;34(1):64-7). (IF:1.785)
  79. Dangat K, Kale A, Joshi S. (2011) Maternal supplementation of omega 3 fatty acids to micronutrient imbalanced diet improves lactation in rat. Metabolism. (2011 Sep;60(9):1318-24). (IF:4.375)
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